Yes. From your profile, go to Main Menu > click on the Zone name for which you would like to block something > Block URLs.
Select the URL Type and input a URL/Pattern to Match. Click on Add URLs.
The other way to block an image or page from our service is to add our ggnoads class to the image or page element; our service will avoid all elements with that class. For more information on our ggnoads class, please visit this page.